Hall published a lengthy critique of Isagenix products in Skeptical Inquirer, in which she said that many of the claims made about the products are false, and that the amount of vitamin A in some of the products is dangerous and goes against the recommendations of The Medical Letter. The company's promotional materials highlight people earning more than $100k per month however, most distributors earn less than 500 dollars per year. Distributors are required to actively recruit new members to earn money. The company also sells 'Financial Wellness' product bundles to their multi-level marketing distributors. Using a multi-level marketing model, Isagenix sells dietary supplement products such as protein shakes, weight loss supplements, and diet snacks and meals, as well as cosmetics. In January 2020, Isagenix International announced its acquisition of Zija International, a multi-level marketing company based in Lehi, Utah. Andrews of Sierra Sciences in September 2011, and the following year launched an “anti-aging” product containing several natural compounds that Sierra Sciences had reportedly verified to have ' telomere-supporting' properties. Isagenix entered into a business arrangement with biologist William H. The recall was voluntarily issued by the company, on FDA recommendations. In February 2009, Isagenix was part of a nationwide recall on peanuts thought to be contaminated with Salmonella, which were used by Isagenix in their Chocolate Dipped Honey Peanut Bar. Jim Coover is chairman and Kathy Coover is the company's executive vice president.

Anderson had previously worked in the nutritional supplement industry and Jim and Kathy Coover had experience in the multi-level marketing industry. Isagenix was founded by John Anderson and Jim and Kathy Coover in 2002.

The Australian consumer organization CHOICE reported that Isagenix's claims about its ' nutritional cleansing' product are scientifically unsupported that its weight loss products are similar in content to much cheaper store-bought alternatives and that its MLM distributors provided unauthorized medical advice. Physician Harriet Hall, writing in the Skeptical Inquirer in 2011, said that many of the claims made about the products are false. According to Isagenix, the company employed 850 people as of 2017. In 2017, the company reported revenues of $958 million. As of 2013 the company reported having over 200,000 active MLM distributors. The company, based in Gilbert, Arizona, was founded in 2002 by John Anderson, Jim Coover, and Kathy Coover. Isagenix International LLC is a privately held multi-level marketing (MLM) company that sells dietary supplements and personal care products.

Isagenix back office